The design of oral controlled drug delivery systems should be primarily aimed to achieve the more predictability and reproducibility to control the drug release, drug concentration in the target tissue and optimization of the therapeutic effect of a drug by controlling its release in the body with lower and less frequent dose. Several controlled release drug delivery strategies have been proposed to overcome these limitations. Although all these approaches improve the oral bio availability of large molecules, none of them offers a complete solution for adequate and safe oral administration. To resolve such kind of problems there are lots of researches are going on. Recently for especially gastrointestinal drug delivery system many changes are come to occur. The recent advance in GIT drug delivery system is gastrointestinal (GIT) patch system for oral drug delivery system. Gastrointestinal patch systems with integrated multifunction could overcome the challenges related to conventional drug delivery. Several gastrointestinal patch systems provide bio-adhesion, drug protection and unidirectional drug release.
Loading....